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Oral cefadroxil prophylaxis in hip fracture surgery. Serum concentrations studied in 17 patients
K S Nungu1, S Bengtsson, C Olerud
1Department of Orthopédics, University Hospital, Uppsala, Sweden.
Acta Orthopaedica Scandinavica
|February 1, 1992
Abstract:
Serum concentration-time curves were determined in seventeen 82 (60-90) year-old patients undergoing trochanteric hip fracture surgery after receiving 1 g of cefadroxil per os. All the patients attained a serum level of antibiotic high enough to inhibit the growth of Staphylococcus aureus and S. epidermidis. When orally administered, cefadroxil should be given within 2 hours before surgery.