Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Urinary Tract Calculi II: Pathophysiology and Clinical Manifestations

Urinary Tract Calculi II: Pathophysiology and Clinical Manifestations

Renal calculi, commonly termed kidney stones, are crystalline solid masses that form in the kidneys but can occur at any point within the urinary system, encompassing the kidneys, ureters, bladder, and urethra.The pathophysiology of renal stones involves several key factors: supersaturation of the urine with stone-forming constituents, changes in urine pH, a decrease in urine volume, and the presence of substances that promote or inhibit stone formation.Supersaturation of Urine: This is the...

Urinary Tract Calculi V: Nursing Management

Urinary Tract Calculi V: Nursing Management

AssessmentSubjective Data: Obtain a detailed health history, including any recent or chronic urinary tract infections, periods of immobilization, previous episodes of renal calculi, and medical conditions such as gout, benign prostatic hyperplasia, or hyperparathyroidism. Review the medication history for drugs that may influence stone formation, including allopurinol, analgesics, loop diuretics, or thiazide diuretics. Document the use of long-term indwelling catheters and any past surgical...

Disorders of the Urinary System

Disorders of the Urinary System

The urinary system is responsible for eliminating waste and excess fluids from the body. However, disorders of the urinary system can arise due to various reasons like infections, stress, age, congenital abnormalities, and lifestyle.
Urinary tract infections (UTIs) are one of the most common urinary system disorders. They are caused by bacteria that enter the urethra and can spread to the bladder resulting in cystitis. Pyelonephritis is the result of a UTI that has ascended to the level of the...

Nursing Assessment of the Genitourinary System II: Inspection and Palpation

Nursing Assessment of the Genitourinary System II: Inspection and Palpation

The nursing assessment of the genitourinary (GU) system involves a systematic inspection and palpation to identify abnormalities in the kidneys, bladder, and surrounding structures.InspectionMouth: Inspect for signs of kidney dysfunction, such as stomatitis (inflammation of the mouth) and ammonia breath, which may occur in advanced kidney disease due to the buildup of urea, breaking down into ammonia.Skin: Check for pallor, which could indicate anemia caused by kidney disease. Look for...

Ascites

Ascites

DefinitionAscites is the buildup of fluid inside the peritoneal cavity. It occurs when fluid moves out of the vascular system faster than the peritoneal lymphatics can remove it. This fluid shift is most commonly seen in liver cirrhosis but can also appear in several other systemic disorders.EtiologyCirrhosis remains the leading cause of ascites. Other conditions that can contribute include:Heart failureConstrictive pericarditisAbdominal cancersNephrotic syndromeSevere protein–calorie...

Intestinal Obstruction II: Pathophysiology

Intestinal Obstruction II: Pathophysiology

Intestinal obstruction triggers a series of physiological responses, starting with gas and fluid accumulation in the bowel segment proximal to the obstruction, leading to distension. This distended intestine compresses the diaphragm, hindering lung expansion and potentially leading to reduced respiratory effort, atelectasis, and pneumonia.To overcome the blockage, the gut intensifies contractions, causing colicky abdominal pain, nausea, and vomiting, which reduces fluid and food intake and...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

In reply: 'Non-criteria' antiphospholipid antibodies and thrombosis.

Cleveland Clinic journal of medicine·2018

Same author

Spontaneous Splenic Rupture in Vascular Ehlers-Danlos Syndrome.

Vascular and endovascular surgery·2015

Same author

A 79-year-old with acute portal vein thrombosis.

Cleveland Clinic journal of medicine·2015

Same author

Association between cardiovascular disease risk factors and occurrence of venous thromboembolism. A time-dependent analysis.

Thrombosis and haemostasis·2012

Same author

Allergic reactions to clopidogrel and cross-reactivity to other agents.

Current allergy and asthma reports·2010

Same author

Severe refractory hypoxemia following a gunshot injury.

Chest·2005

Search research articles

Related Experiment Video

Updated: Jul 16, 2026

An Immature Murine Model of Reversible Unilateral Ureteral Obstruction

An Immature Murine Model of Reversible Unilateral Ureteral Obstruction

Published on: April 4, 2025

Leg swelling due to urinary obstruction.

Juzar Lokhandwala¹, Heather Gornik

¹Section of Vascular Medicine, Department of Cardiovascular Medicine, The Cleveland Clinic Foundation, Cleveland, OH 44195, USA.

Vascular Medicine (London, England)

|March 30, 2007

Summary

A distended bladder can obstruct leg veins, causing swelling and incontinence. Promptly relieving urinary obstruction can reverse this venous issue and leg edema.

Area of Science:

Vascular Medicine
Urology

Background:

Lower extremity edema is a common clinical presentation.
Venous duplex ultrasound is a standard diagnostic tool for venous obstruction.

Observation:

An 85-year-old male presented with bilateral leg edema and urinary incontinence.
Abdominal examination revealed a severely distended bladder.
Venous duplex demonstrated bilateral monophasic waveforms in proximal lower extremity veins, indicating obstruction.

Findings:

Relief of urinary obstruction led to the return of normal venous flow patterns.
Improvement in leg swelling was observed after urinary decompression.
The findings suggest non-thrombotic obstruction of proximal lower extremity veins by an enlarged bladder.

More Related Videos

Unilateral Ureteral Obstruction Model for Investigating Kidney Interstitial Fibrosis

Unilateral Ureteral Obstruction Model for Investigating Kidney Interstitial Fibrosis

Published on: April 25, 2025

Point-of-Care Kidney and Genitourinary Ultrasound in Adults: Image Acquisition

Point-of-Care Kidney and Genitourinary Ultrasound in Adults: Image Acquisition

Published on: June 21, 2024

Related Experiment Videos

Last Updated: Jul 16, 2026

An Immature Murine Model of Reversible Unilateral Ureteral Obstruction

An Immature Murine Model of Reversible Unilateral Ureteral Obstruction

Published on: April 4, 2025

Unilateral Ureteral Obstruction Model for Investigating Kidney Interstitial Fibrosis

Unilateral Ureteral Obstruction Model for Investigating Kidney Interstitial Fibrosis

Published on: April 25, 2025

Point-of-Care Kidney and Genitourinary Ultrasound in Adults: Image Acquisition

Point-of-Care Kidney and Genitourinary Ultrasound in Adults: Image Acquisition

Published on: June 21, 2024

Implications:

An enlarged bladder is an infrequent but reversible cause of lower extremity edema.
Careful interpretation of Doppler waveforms is crucial for diagnosing bladder-induced venous obstruction.
This highlights the importance of considering urological causes in patients with unexplained venous findings.