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Depression and anxiety: pharmacological treatment in general practice
Steven Ellen1, Rob Selzer, Trevor Norman
1Consultation-Liaison Psychiatry, The Alfred Hospital, Melbourne, Victoria, Australia. s.ellen@alfred.org.au
Background:
Depression and anxiety are common presentations in general practice and medications are one of the key treatment strategies.
Objective:
This article provides an overview of important practical issues to consider when prescribing medications for anxiety and depression.
Discussion:
Key questions for the general practitioner to consider are: Are medications the best option? Which is the best medication for this patient? What are the practical aspects of prescribing this medication? What is the next step if it doesn't work?
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Anxiolytic Drugs: Overview
Primary Types of Anxiolytic Drugs
1. Benzodiazepines:
Benzodiazepines bind to the GABA-A receptor in the brain, enhancing GABA's interaction. This action reduces neurotransmission, effectively blocking anxiety-associated limbic circuitry.
Drug Therapy
Antianxiety Medications
Anxiolytic Drugs: Benzodiazepines and Buspirone
Antidepressant Drugs: MAOIs and Other Agents
Antidepressant Drugs: Overview
Antidepressant Drugs: Tricyclics, SSRIs, and SNRIs
