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Related Experiment Videos

Magnetic resonance imaging contrast agents.

V M Runge

    Current Opinion in Radiology
    |February 1, 1992
    PubMed
    Summary

    Intravenous contrast enhancement is crucial for head and spine MR imaging. New gadolinium-based contrast agents are emerging, expanding clinical applications and future functional assessments.

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    [Comparison of contrast behavior of gadobenate-dimeglumine and Gd-DTPA in intra-axial brain tumors. A double-blind randomized intraindividual cross-over study].

    Der Radiologe·2002

    Area of Science:

    • Radiology
    • Medical Imaging

    Background:

    • Intravenous contrast enhancement is a key technique in Magnetic Resonance (MR) imaging, especially for neurological applications involving the head and spine.
    • Gadolinium-based contrast agents (GBCAs) with extracellular distribution are widely used in clinical practice.

    Discussion:

    • The current landscape includes gadopentetate dimeglumine as the sole FDA-approved agent in the US.
    • Emerging chelates like gadoteridol are nearing approval, indicating advancements in contrast agent technology.

    Key Insights:

    • Clinical applications of GBCAs have significantly expanded.
    • Newer agents are expected to offer improved safety profiles and diagnostic capabilities.

    Outlook:

    • Further approvals of novel GBCAs are anticipated within the next decade.
    • These upcoming agents hold potential for assessing tissue function, moving beyond anatomical imaging.

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