Related Experiment Video
Updated: Jul 15, 2026

Modified MicroSecure Vitrification: A Safe, Simple and Highly Effective Cryopreservation Procedure for Human Blastocysts
Published on: March 2, 2017
Vinyl bags prevent hypothermia at birth in preterm infants
Bobby Mathew1, Satyan Lakshminrusimha, Katherine Cominsky
1Division of Neonatology, Department of Pediatrics, Women and Children's Hospital of Buffalo, Buffalo, USA.
Objective:
To compare the effect of standard care vs. the use of vinyl bags (Vi-Drape (R) isolation bag) on admission temperature in extremely premature infants < or = 28 weeks gestational age at birth.
Methods:
Twenty seven premature infants with similar baseline characteristics were assigned and placed in vinyl bags (n=14) immediately following delivery without drying or received standard care (controls, n=13), including drying and placement under a radiant warmer. Axillary temperature was recorded on admission to the neonatal unit.
Results:
The average temperature in the vinyl bag group was significantly higher (35.9 +/- 0.13 vs 34.9 +/- 0.24 degrees C, p=0.002). Although the cord blood pH was similar between the two groups (7.33+0.02 in the vinyl bag group and 7.33 +/- 0.01 in the control group), the worst pH in the first 6 hours of life was significantly lower in the control group (7.32 +/- 0.02 vs 7.22 +/- 0.04, p=0.03). There was a significant increase in maximal oxygen requirement during the first 24 h in the control group (82.9 vs 43.3% in the vinyl bag group, p=0.0004).
Conclusion:
Vinyl bags prevent heat loss and are a simple and effective intervention in preventing hypothermia in the delivery room and early acidosis in premature infants.

