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Updated: Jul 15, 2026
07:05
Behavioral Disturbances: An Innovative Approach to Monitor the Modulatory Effects of a Nutraceutical Diet
Published on: January 3, 2017
[On the active agents of valerian]
1Kali-Chemie AG, Sparte Pharma, D-3000 Hannover, Bundesrepublik Deutschland.
Planta Medica
|January 1, 1981
Summary
Carbon-13 Nuclear Magnetic Resonance (C13-NMR) shifts in valepotriates are highly dependent on acyloxy substituents. This study clarifies the structures of known and novel valepotriates using these characteristic shifts.
Area of Science:
- Organic Chemistry
- Natural Product Chemistry
- Spectroscopy
Context:
- Valepotriates are iridoid esters found in plants like Valeriana officinalis.
- Their structural elucidation is crucial for understanding their biological activities.
- Nuclear Magnetic Resonance (NMR) spectroscopy is a key tool for characterizing organic molecules.
Purpose:
- To investigate the relationship between C13-NMR chemical shifts and the structural features of valepotriates.
- To utilize C13-NMR spectroscopy for the identification and structural determination of known and new valepotriates.
Summary:
- C13-NMR chemical shifts of valepotriates exhibit characteristic dependencies on the type and position of acyloxy substituents.
- Specific shifts correlate with variations in ester groups and their locations on the valepotriate skeleton.
- The study successfully clarified the structures of several known and previously undescribed valepotriates.
Impact:
- Provides a reliable spectroscopic method for valepotriate structure determination.
- Facilitates the discovery and characterization of new natural products.
- Contributes to the chemotaxonomic understanding of plants containing valepotriates.
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