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Comprehensive Evaluation of the Effectiveness and Safety of Placenta-Targeted Drug Delivery Using Three Complementary Methods
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[Transplacental effects of bemithyl]

L I Bugaeva, T D Denisova, A A Spasov

    Eksperimental'Naia I Klinicheskaia Farmakologiia
    |April 4, 2007
    PubMed

    The daily administration of bemithyl (20 mg/kg) from 6 th to 16 th day of pregnancy in female rats led to the decrease in fetal death after the implantation and increased fetal body weight. The treatment of pregnant rats also led to acceleration of the development of physical condition and sensomotor reflexes of progeny in the postnatal period.

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