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Vertebral polyostotic lymphoma in a young dog
Marta Vascellari1, Silvia Tasca, Tommaso Furlanello
1Histopathology Department, Istituto Zooprofilattico Sperimentale delle Venezie, 35020 Legnaro (PD), Italy. mvascellari@izsvenezie.it
Summary
A rare case of canine lymphoma affecting the spine is presented. This T-cell lymphoma caused unusual bone lesions and neurological signs in a Golden Retriever.
Area of Science:
- Veterinary Oncology
- Canine Pathology
Background:
- Lymphoma is a common cancer in dogs, but bone involvement is rare.
- This case highlights an unusual presentation of lymphoma with significant vertebral lesions.
Observation:
- A 20-month-old Golden Retriever exhibited progressive paraparesis and anorexia.
- Diagnostic imaging revealed ventral fusion of lumbar vertebrae with new bone formation.
- Bloodwork showed pancytopenia and hypercalcemia.
Findings:
- Neoplastic lymphoid cells infiltrated lymph nodes, bone marrow, liver, kidney, and vertebrae.
- Histopathology confirmed a polyostotic and medullary T-cell lymphoma with spondylosis.
- The tumor cells exhibited scant cytoplasm and round, hyperchromatic nuclei.
Implications:
- This case expands the understanding of lymphoma's diverse clinical presentations in dogs.
- The association of lymphoma with osteoproductive vertebral lesions is noteworthy.
- Further research into bone-specific lymphoma in canines is warranted.
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