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Published on: July 20, 2022
[Prototheca Wickerhami peritonitis in patients on peritoneal dialysis]
C Pérez Melón1, M Camba, A Tinajas
1Servicio de Nefrología, Compexo Hospitalario Ourense. eir@inicia.es
Summary
This study details a successful treatment for Prototheca peritonitis, a rare infection in peritoneal dialysis patients. The approach combined antifungal medications with catheter removal for a positive outcome.
Area of Science:
- Medical Mycology
- Infectious Diseases
- Nephrology
Background:
- Prototheca species are ubiquitous environmental organisms.
- Human infections (protothecosis) are rare, typically affecting skin or subcutaneous tissues.
- Disseminated disease and urinary tract infections are infrequently reported.
Observation:
- Prototheca wickerhamii is the most common species causing human infections.
- Peritonitis is a rare but serious complication in patients undergoing peritoneal dialysis.
- Few cases of Prototheca peritonitis in peritoneal dialysis patients have been documented.
Findings:
- This report describes a successful treatment regimen for Prototheca peritonitis in a peritoneal dialysis patient.
- The treatment involved a combination of antifungal agents: amphotericin and itraconazole.
- Surgical removal of the peritoneal dialysis catheter was a critical component of the successful management strategy.
Implications:
- This case highlights a viable therapeutic approach for managing rare Prototheca peritonitis in immunocompromised or dialysis patients.
- Early diagnosis and combined treatment (antifungals plus catheter removal) may improve patient outcomes.
- Further research into optimal treatment strategies for invasive protothecal infections is warranted.
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