Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Diffusion-weighted imaging in normal fetal brain maturation.

J F Schneider1, S Confort-Gouny, Y Le Fur

  • 1Department of Pediatric Radiology, University Children's Hospital UKBB, Basel, Switzerland. jacques.schneider@ukbb.ch

European Radiology
|April 4, 2007
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Real-world 5-year outcomes with durvalumab after chemoradiotherapy in unresectable stage III NSCLC.

ESMO open·2026
Same author

Prenatal small head circumference: Which biomarkers best predict microcephaly?

Early human development·2026
Same author

AFSOS-SFRO Guidelines on Radiation-Induced Lung Injury.

Clinical lung cancer·2025
Same author

Efficacy of first-line treatments for advanced pulmonary sarcomatoid carcinomas: a real-world analysis.

ESMO open·2025
Same author

The European Prospective Investigation into Cancer and Nutrition Cohort (EPIC): a gateway to rare cancer epidemiological research.

ESMO rare cancers·2025
Same author

[Place adjuvant targeted therapies during localized NSCLC].

Bulletin du cancer·2025
Same journal

The bMRI-QUAL scoring system: an important first step toward standardizing breast MRI quality.

European radiology·2026
Same journal

Spectral CT-based habitat analysis for predicting pathologic response to neoadjuvant therapy in gastric cancer.

European radiology·2026
Same journal

MR-guided microwave ablation of liver tumors: outcomes in local tumor control and determinants of treatment success.

European radiology·2026
Same journal

AI integration in pediatric radiology: perspectives from international academic leaders.

European radiology·2026
Same journal

Association of hypertension and blood pressure control with aneurysm wall enhancement in unruptured intracranial aneurysms: a multicenter propensity score-matched study.

European radiology·2026
Same journal

Conservative management of < 3cm anterior mediastinal lesions in lung cancer screening is safe.

European radiology·2026
See all related articles

This study tracked fetal brain development using diffusion-weighted imaging (DWI). Apparent diffusion coefficient (ADC) values reveal distinct maturation patterns in different brain regions throughout gestation.

Area of Science:

  • Neuroimaging
  • Fetal Development
  • Biomedical Engineering

Background:

  • Diffusion-weighted imaging (DWI) offers insights into tissue maturation beyond conventional MRI.
  • Understanding fetal brain development in utero is crucial for identifying neurological abnormalities.

Purpose of the Study:

  • To analyze the longitudinal changes in apparent diffusion coefficient (ADC) values of the normal fetal brain in utero.
  • To establish normative data for fetal brain maturation using DWI.

Main Methods:

  • Diffusion-weighted imaging (DWI) was performed on 78 fetuses between 23 and 37 gestational weeks.
  • Apparent diffusion coefficient (ADC) values were measured in various fetal brain regions, including deep white matter, lobes, cerebellum, brainstem, basal ganglia, and thalamus.
  • Neurological outcomes were assessed postnatally to ensure a healthy cohort.

Related Experiment Videos

Main Results:

  • Significant regional variations in ADC values were observed, with supratentorial deep white matter showing higher values than the cerebellum and brainstem.
  • A linear negative correlation between ADC values and gestational age was noted in the brainstem, cerebellar hemisphere, and thalamus.
  • Supratentorial regions exhibited an initial increase in ADC values, followed by a decrease after 30 gestational weeks, indicating complex maturation processes.

Conclusions:

  • This study provides essential normative data for fetal brain maturation in utero, utilizing apparent diffusion coefficient (ADC) measurements.
  • The findings offer novel insights into the dynamic changes of brain development during gestation, not previously documented in premature infants.