Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Pseudolaric acids from Pseudolarix kaempferi.

B N Zhou1, B P Ying, G Q Song

  • 1Shanghai Institute of Materia medica, Chinese Academy of Sciences, China.

Planta Medica
|January 1, 1983
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

[Clinical features and efficacy analysis of different treatment modalities for type Ⅰ and Ⅱ spontaneous extracranial carotid artery dissection].

Zhonghua yi xue za zhi·2026
Same author

[Research status of glucagon-like peptide-1 receptor agonists on obstructive sleep apnea].

Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases·2024
Same author

[Clinical characteristics and efficacy analysis of various treatments for spontaneous carotid artery dissection].

Zhonghua yi xue za zhi·2024
Same author

Difference Analysis Based on 16S rRNA Sequencing of Different Soil Bacterial Communities.

Fa yi xue za zhi·2019
Same author

Progress in the 16S rRNA Gene Sequencing in Forensic Science.

Fa yi xue za zhi·2018
Same author

Determination of the potential of induced pluripotent stem cells to differentiate into mouse nucleus pulposus cells in vitro.

Genetics and molecular research : GMR·2015
Same journal

Application of High Throughput Sequencing in the authentication and quality control of herbal material and products.

Planta medica·2026
Same journal

Leveraging Biochemometrics to Prioritize Biologically Relevant Compounds from Natural Product Mixtures: A Journey from Conception to Successful Outcomes.

Planta medica·2026
Same journal

New Serratane Triterpenoid and Musashi2 inhibitors from Huperzia serrata.

Planta medica·2026
Same journal

Phytochemicals to Pharmacology: Potential Cytotoxic and Tumor Inhibitory Activity of Elaeocarpus ganitrus Extract in Preclinical Models.

Planta medica·2026
Same journal

Edible Plants with Antimicrobial Potential - Report of the Expert Meetings from Ibero-American Countries.

Planta medica·2026
Same journal

Ginsenoside Rd ameliorates glucose metabolism by regulating GLP-1/ MAPK/ NF-κB signaling pathway in db/db mice.

Planta medica·2026
See all related articles

Three new compounds, pseudolaric acids A, B, and C, were isolated from Pseudolarix kaempferi. These compounds show antifungal activity, with pseudolaric acid B also exhibiting an antifertility effect.

Area of Science:

  • Phytochemistry
  • Natural Products Chemistry
  • Pharmacology

Background:

  • Pseudolarix kaempferi root bark is utilized in traditional Chinese medicine for its antifungal properties.
  • Diterpenoids are a class of natural products with diverse biological activities.

Purpose of the Study:

  • To isolate and characterize novel diterpenoids from Pseudolarix kaempferi.
  • To evaluate the antifungal and antifertility activities of the isolated compounds.

Main Methods:

  • Extraction and isolation of compounds from Pseudolarix kaempferi root bark.
  • Structure elucidation using spectral data (NMR, MS) and chemical methods.
  • Bioassays to determine antifungal and antifertility effects.

Main Results:

Related Experiment Videos

  • Three novel diterpenoids, pseudolaric acids A, B, and C, were successfully isolated.
  • The structures of pseudolaric acids B and C were determined to be compounds 1 and 6, respectively.
  • Pseudolaric acids A, B, and C demonstrated significant antifungal activity.
  • Pseudolaric acid B exhibited a notable antifertility effect.

Conclusions:

  • Pseudolarix kaempferi is a source of novel diterpenoids with promising biological activities.
  • Pseudolaric acids A, B, and C represent potential new antifungal agents.
  • Pseudolaric acid B warrants further investigation for its antifertility properties.