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Updated: Jul 15, 2026

Optimized Management of Endovascular Treatment for Acute Ischemic Stroke
Published on: January 18, 2018
Outcomes after first-ever stroke
C M Cheung1, T H Tsoi, Sonny F K Hon
1Department of Medicine, Pamela Youde Nethersole Eastern Hospital, Chai Wan, Hong Kong. chun-ming@graduate.hku.hk
Insights
Outcomes after first-ever stroke are poor, with high mortality and recurrence rates within five years. Many stroke survivors experience long-term dependence, highlighting the need for improved stroke care and prevention strategies.
Area of Science:
- Neurology
- Epidemiology
- Public Health
Background:
- First-ever stroke outcomes significantly impact patient prognosis and healthcare systems.
- Understanding long-term stroke sequelae is crucial for effective patient management and resource allocation.
Purpose of the Study:
- To determine the long-term outcomes of first-ever stroke, focusing on mortality, recurrence, and functional dependence.
- To provide data on stroke prognosis for a regional hospital cohort in Hong Kong.
Main Methods:
- Retrospective analysis of a prospectively collected cohort of 755 patients with first-ever stroke (1996-1998).
- Assessment of mortality, stroke recurrence, and dependence in activities of daily living at 30 days, 1 year, and 5 years post-stroke.
Main Results:
- Five-year mortality rate was 39.7%.
- Five-year stroke recurrence rate was 21.2%, with varied patterns for ischemic and hemorrhagic strokes.
- 10.7% of patients were dependent in activities of daily living at 5 years.
Conclusions:
- Long-term prognosis after a first-ever stroke is generally poor.
- A significant proportion of stroke survivors face mortality, recurrence, and functional disability within five years.
- Findings underscore the critical need for enhanced stroke prevention and rehabilitation strategies.
Objectives:
To determine the outcomes after first-ever stroke, including mortality, dependence, and recurrence.
Design:
Retrospective study on a prospectively collected cohort.
Setting:
Regional hospital, Hong Kong.
Patients:
A cohort of 755 patients presented to our hospital from 1996 to 1998 with their first-ever stroke.
Main Outcome Measures:
Mortality and stroke recurrence rate at 30 days, 1 year, and 5 years from the onset of the stroke. Dependence in activity of daily living at 5 years from the onset of stroke.
Results:
The mortality rate was 15.1% at 30 days, 22.5% at 1 year, and 39.7% at 5 years from the onset of the first-ever stroke. The rate of stroke recurrence was 0.9% at 30 days, 7.0% at 1 year, and 21.2% at 5 years from the onset of first-ever stroke. Among patients presenting with ischaemic strokes, 109 (20.6%) had a recurrence, of which 92 (84%) were ischaemic strokes and 17 (16%) were haemorrhagic. Among patients presenting with intracerebral haemorrhage, 25 (23.1%) had a recurrence, of which 12 (48%) were haemorrhagic strokes and 13 (52%) patients were ischaemic. After 5 years, 11% of the patients were dependent in terms of activity of daily living.
Conclusions:
The long-term prognosis after first-ever stroke is poor--5 years after their stroke, 39.7% of patients had died and 10.7% were dependent in terms of activity of daily living; 136 (21%) who survived at least 30 days after the initial stroke, had a recurrence within 5 years.
Related Concept Videos
Ischemic Stroke l: Introduction
Hemorrhagic Stroke l: Introduction
Ischemic Stroke ll: Pathophysiology
