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Related Concept Videos

Targeted Cancer Therapies02:57

Targeted Cancer Therapies

The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against specific...
Targeted Cancer Therapies02:57

Targeted Cancer Therapies

The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against specific...
Adaptive Mechanisms in Cancer Cells02:53

Adaptive Mechanisms in Cancer Cells

Cancer cells accumulate genetic changes at an abnormally rapid rate due to the defects in the DNA repair mechanisms. From an evolutionary perspective, such genetic instability is advantageous for cancer development. Mutant cell lines accumulate a series of beneficial mutations that contribute to their progression into cancer.
Some of the advantages that cancer cells have on normal cells include - enhanced ability to divide without terminally differentiating, induce new blood vessel formation,...
Treatment Resistant Cancers02:56

Treatment Resistant Cancers

Cancer is the second leading cause of death in the United States. A cancer cell is genetically unstable and hence can mutate faster. They can also modify their microenvironment and escape immune surveillance. The difficulties in treating cancer are further compounded by the emergence of rapid resistance to anticancer drugs. The most common ways to attain resistance in cancer cells include alteration in drug transport and metabolism, modification of drug target, elevated DNA damage response, or...
Combination Therapies and Personalized Medicine02:50

Combination Therapies and Personalized Medicine

Combining two or more treatment methods increases the life span of cancer patients while reducing damage to vital organs or tissue from the overuse of a single treatment. Combination therapy also targets different cancer-inducing pathways, thus reducing the chances of developing resistance to treatment.
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...

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Related Experiment Video

Updated: Jul 15, 2026

Surface-enhanced Resonance Raman Scattering Nanoprobe Ratiometry for Detecting Microscopic Ovarian Cancer via Folate Receptor Targeting
07:54

Surface-enhanced Resonance Raman Scattering Nanoprobe Ratiometry for Detecting Microscopic Ovarian Cancer via Folate Receptor Targeting

Published on: March 25, 2019

Exploiting nanotechnology to target cancer.

S Sengupta1, R Sasisekharan

  • 1BWH-HST Center for Biomedical Engineering, Department of Medicine, Brigham and Women's Hospital, Cambridge, MA 02139, USA. shiladit@MIT.edu

British Journal of Cancer
|April 5, 2007
PubMed
Summary

Nanotechnology offers new ways to manage cancer, improving early detection, tumor imaging, and drug delivery. This review explores key advancements and future directions in nanoscale cancer care.

Area of Science:

  • Oncology
  • Materials Science
  • Biotechnology

Background:

  • Cancer management is evolving with technological integration.
  • Nanotechnology provides novel tools for oncological applications.
  • Current approaches face limitations addressed by nanoscale innovations.

Purpose of the Study:

  • To review major milestones in integrating nanotechnology with cancer biology.
  • To discuss the future of nanoscale approaches in cancer management.
  • To highlight the impact of nanodevices on cancer detection, imaging, and therapy.

Main Methods:

  • Literature review of nanotechnology applications in oncology.
  • Analysis of nanoscale devices for cancer detection (nanocantilevers, nanoparticles).
  • Evaluation of nanoparticles for tumor imaging (radiocontrast, quantum dots).

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Polymalic Acid-based Nano Biopolymers for Targeting of Multiple Tumor Markers: An Opportunity for Personalized Medicine?

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In Vivo Targeting of Xenografted Human Cancer Cells with Functionalized Fluorescent Silica Nanoparticles in Zebrafish
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In Vivo Targeting of Xenografted Human Cancer Cells with Functionalized Fluorescent Silica Nanoparticles in Zebrafish

Published on: May 8, 2020

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Last Updated: Jul 15, 2026

Surface-enhanced Resonance Raman Scattering Nanoprobe Ratiometry for Detecting Microscopic Ovarian Cancer via Folate Receptor Targeting
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Published on: March 25, 2019

Polymalic Acid-based Nano Biopolymers for Targeting of Multiple Tumor Markers: An Opportunity for Personalized Medicine?
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Polymalic Acid-based Nano Biopolymers for Targeting of Multiple Tumor Markers: An Opportunity for Personalized Medicine?

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In Vivo Targeting of Xenografted Human Cancer Cells with Functionalized Fluorescent Silica Nanoparticles in Zebrafish
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In Vivo Targeting of Xenografted Human Cancer Cells with Functionalized Fluorescent Silica Nanoparticles in Zebrafish

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  • Assessment of nanovectors and hybrid nanoparticles for drug delivery.

    • Main Results:

    • Nanoscale devices are impacting cancer biology across multiple levels.
    • Significant progress has been made in early cancer detection using nanotechnology.
    • Nanoparticles enhance tumor imaging accuracy and drug delivery efficiency.
    • Hybrid nanoparticles offer versatile platforms for cancer treatment.

    Conclusions:

    • Nanotechnology is a transformative force in modern cancer management.
    • Future research will likely focus on refining nanovector design and targeted delivery.
    • Continued integration of nanotechnology promises improved patient outcomes in oncology.