Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Endocarditis I: Introduction01:25

Endocarditis I: Introduction

Introduction:Endocarditis is the infection of the endocardium, the inner lining of the heart and its valves. When the heart muscle is involved, the condition is termed myocarditis, while an infection of the outer lining is called pericarditis. Infective endocarditis (IE) primarily affects the endocardium, where pathogens adhere to the valves or lining, forming vegetation that can lead to severe complications. Infective endocarditis occurs when microorganisms, usually bacteria from other body...
Endocarditis III: Medical Management01:18

Endocarditis III: Medical Management

Infective endocarditis management involves a multifaceted approach encompassing infection prevention, lifestyle modifications, pharmacological therapy, and surgical management.Infection Prevention:Hand Hygiene: Thorough handwashing is crucial to prevent the spread of infection. Hand hygiene should be performed regularly, especially before and after using the restroom.Oral Hygiene: Good oral hygiene is essential. It includes brushing teeth immediately after waking up and before bed, flossing...
Aneurysm III: Interprofessional Care01:26

Aneurysm III: Interprofessional Care

Aneurysm management involves either conservative medical therapy or surgical intervention, depending on the size and symptoms of the aneurysm. Conservative management is generally reserved for smaller, asymptomatic aneurysms, while larger or symptomatic aneurysms often necessitate surgical repair.Conservative Medical TherapyFor small, asymptomatic aneurysms, particularly abdominal aortic aneurysms (AAA) less than 5.5 centimeters in diameter, conservative medical therapy is recommended. This...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Surgical Site Infection in Lung Transplantation: Clinical Impact and Predictive Factors: Analysis From the Portuguese Lung Transplantation Center.

Transplantation proceedings·2026
Same author

Descending Necrotizing Mediastinitis: A 7-Year Single-Centre Experience.

Portuguese journal of cardiac thoracic and vascular surgery·2026
Same author

Neglected tropical diseases elimination activities in South Sudan's largest refugee camp: lessons from 2 years of work.

International health·2026
Same author

Neglected tropical diseases in conflict-related humanitarian emergency settings: a systematic review of the literature.

International health·2026
Same author

The 2025 Accra Declaration on Upskilling and Cost- Effective Cardiac Surgery in Africa.

Asian cardiovascular & thoracic annals·2026
Same author

Reducing filth fly populations and transmission of diarrhoeal pathogens in harsh settings: study protocol for a cross-over trial in South Sudan.

BMC infectious diseases·2026

Related Experiment Video

Updated: Jul 15, 2026

Full-root Aortic Valve Replacement by Stentless Aortic Xenografts in Patients with Small Aortic Roots
12:17

Full-root Aortic Valve Replacement by Stentless Aortic Xenografts in Patients with Small Aortic Roots

Published on: May 21, 2017

Allograft aortic root replacement in complex prosthetic endocarditis.

Sérgio Lopes1, Paulo Calvinho, Ferrão de Oliveira

  • 1Cardiothoracic Surgery, University Hospital, Coimbra, Portugal.

European Journal of Cardio-Thoracic Surgery : Official Journal of the European Association for Cardio-Thoracic Surgery
|April 6, 2007
PubMed
Summary

Allograft aortic root replacement is effective for complex prosthetic valve endocarditis, showing low infection recurrence and good long-term survival. This surgical approach offers superior outcomes compared to other valve substitutes.

More Related Videos

Standardized Technique of Aortic Valve Re-implantation for Valve-sparing Aortic Root Replacement
14:14

Standardized Technique of Aortic Valve Re-implantation for Valve-sparing Aortic Root Replacement

Published on: December 11, 2017

Implantation of the Syncardia Total Artificial Heart
16:11

Implantation of the Syncardia Total Artificial Heart

Published on: July 18, 2014

Related Experiment Videos

Last Updated: Jul 15, 2026

Full-root Aortic Valve Replacement by Stentless Aortic Xenografts in Patients with Small Aortic Roots
12:17

Full-root Aortic Valve Replacement by Stentless Aortic Xenografts in Patients with Small Aortic Roots

Published on: May 21, 2017

Standardized Technique of Aortic Valve Re-implantation for Valve-sparing Aortic Root Replacement
14:14

Standardized Technique of Aortic Valve Re-implantation for Valve-sparing Aortic Root Replacement

Published on: December 11, 2017

Implantation of the Syncardia Total Artificial Heart
16:11

Implantation of the Syncardia Total Artificial Heart

Published on: July 18, 2014

Area of Science:

  • Cardiovascular Surgery
  • Infectious Diseases
  • Transplantation Immunology

Background:

  • Complex prosthetic valve endocarditis (PVE) with root abscess or periprosthetic leak presents significant surgical challenges.
  • Traditional treatments for PVE often have high morbidity and mortality rates.

Purpose of the Study:

  • To evaluate the perioperative and long-term outcomes of allograft aortic root replacement in patients with complicated PVE.
  • To assess the efficacy and safety of using allografts for complex PVE cases.

Main Methods:

  • A cohort of 41 patients with PVE and complications underwent fresh allograft valve replacement with root replacement.
  • Patients were followed for a mean of 54.3 months, with endpoints including death or allograft failure.
  • Key patient characteristics such as age, NYHA class, prosthesis type, and comorbidities were recorded.

Main Results:

  • The study reported a low in-hospital mortality rate of 4.8% and transient renal failure in 22.0% of patients.
  • Late mortality occurred in 19.5% of patients due to various causes, with no recurrence of endocarditis observed.
  • The 10-year survival rate was 79%, and only two patients required reoperation for allograft failure.

Conclusions:

  • Allograft aortic root replacement is associated with low morbidity and mortality in complex PVE.
  • This technique demonstrated no recurrence of infection and yielded superior results compared to other valvular substitutes in this series.