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Related Concept Videos

Esophageal Perforation-II: Clinical Manifestations and Management01:28

Esophageal Perforation-II: Clinical Manifestations and Management

Esophageal perforations manifest in various clinical forms, influenced by factors such as the perforation's cause and location (cervical, intrathoracic, or intra-abdominal), the extent of contamination, and potential injury to adjacent mediastinal structures. The timing between the perforation occurrence and treatment initiation also affects the clinical presentation.
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Related Experiment Video

Updated: May 21, 2026

Laparoscopic Anterior Right Hepatectomy: A Single-Center Experience
09:51

Laparoscopic Anterior Right Hepatectomy: A Single-Center Experience

Published on: December 4, 2023

Descending Necrotizing Mediastinitis: A 7-Year Single-Centre Experience.

Catarina Pereira Moita1, Catarina Figueiredo1, Zenito Cruz1

  • 1Thoracic Surgery Department - Hospital de Santa Marta, Unidade Local de Saúde São José, Portugal.

Portuguese Journal of Cardiac Thoracic and Vascular Surgery
|May 19, 2026
PubMed
Summary

Descending necrotizing mediastinitis (DNM) requires prompt diagnosis and surgical intervention. This study found that a multidisciplinary approach led to favorable outcomes with low morbidity and no mortality in 14 patients.

Keywords:
Descending Necrotizing MediastinitisSurgical DrainageThoracic SurgeryTranscervical DrainageTransthoracic Drainage

Related Experiment Videos

Last Updated: May 21, 2026

Laparoscopic Anterior Right Hepatectomy: A Single-Center Experience
09:51

Laparoscopic Anterior Right Hepatectomy: A Single-Center Experience

Published on: December 4, 2023

Area of Science:

  • Thoracic Surgery
  • Infectious Diseases
  • Critical Care Medicine

Background:

  • Descending necrotizing mediastinitis (DNM) is a severe complication of head and neck infections.
  • DNM rapidly progresses to the mediastinum, posing a life-threatening risk.
  • Early diagnosis and surgical intervention are crucial for survival.

Purpose of the Study:

  • To present the clinical experience and management strategies for DNM.
  • To evaluate the outcomes of surgical treatment for DNM.

Main Methods:

  • Retrospective analysis of 14 adult patients with DNM treated between 2017 and 2023.
  • Surgical treatment involved cervical and thoracic procedures.
  • Computed tomography scans were used for diagnosis.

Main Results:

  • The majority of patients (12/14) progressed to stage II DNM.
  • Pharyngeal (7), cervical (5), and odontogenic (2) infections were primary sites.
  • A median of 2 cervical and 1 thoracic intervention per patient was performed, with combined cervicotomy and thoracotomy as the preferred approach.

Conclusions:

  • Effective DNM management requires early CT diagnosis, antibiotics, and urgent surgical drainage.
  • A multidisciplinary approach is vital for successful outcomes.
  • This study demonstrated low long-term morbidity and no mortality in DNM patients.