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Updated: Jul 15, 2026

In Situ Hybridization Techniques for Paraffin-Embedded Adult Coral Samples
Published on: August 31, 2018
Terpenoid-related metabolites from a formosan soft coral Nephthea chabrolii
Jui-Hsin Su1, Chang-Feng Dai, Hsin-Hui Huang
1Department of Marine Biotechnology and Resources, National Sun Yat-sen University, Kaoshiung, Taiwan, R.O.C.
Abstract:
Two new sesquiterpenoidal natural products chabrolidiones A and B (1 and 2), two C(18) terpenoid-related carboxylic acids, ketochabrolic acid (3) and isoketochabrolic acid (4), and one naphthoquinone derivative chabrolonaphthoquinone C (5), along with two known compounds (+)-aristolone (6) and teuhetenone A (7) were isolated from a Formosan soft coral Nephthea chabrolii. The structures of the new metabolites were determined on the basis of extensive spectroscopic analysis and by comparison of NMR data with those of related metabolites. Metabolite 1 has been synthesized previously, but was isolated for the first time from natural sources. Cytotoxic activity of metabolites 1-3 and 5-7 against a limited panel of cancer cell lines is also described.
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