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Related Concept Videos

Cancer Vaccines01:30

Cancer Vaccines

Cancer treatment vaccines are a rapidly evolving field that offers a promising approach to immunotherapy. Unlike traditional vaccines that prevent diseases, cancer treatment vaccines are designed to treat existing cancers by stimulating the immune system to recognize and attack cancer cells.
Cancer vaccines come in two categories: preventive (prophylactic) and treatment (active). Preventive vaccines, such as the Human Papillomavirus (HPV) vaccine, protect against viruses that cause certain...
Vaccinations01:51

Vaccinations

Overview
Rous Sarcoma Virus (RSV) and Cancer01:03

Rous Sarcoma Virus (RSV) and Cancer

Rous Sarcoma virus or RSV was discovered by F. Peyton Rous in the year 1911 as a filterable transmissible agent that could cause tumors in chickens. He won a Nobel Prize for this discovery in 1966. His experiments clearly demonstrated that some cancers could be caused by infectious agents and led to the discovery of many more cancer-causing viruses in animals as well as humans.
RSV is a retrovirus that contains two copies of a plus-strand  RNA genome. Its genome consists of four main open...
Rous Sarcoma Virus (RSV) and Cancer01:03

Rous Sarcoma Virus (RSV) and Cancer

Rous Sarcoma virus or RSV was discovered by F. Peyton Rous in the year 1911 as a filterable transmissible agent that could cause tumors in chickens. He won a Nobel Prize for this discovery in 1966. His experiments clearly demonstrated that some cancers could be caused by infectious agents and led to the discovery of many more cancer-causing viruses in animals as well as humans.
RSV is a retrovirus that contains two copies of a plus-strand  RNA genome. Its genome consists of four main open...
Other Pulmonary Disorders01:17

Other Pulmonary Disorders

Respiratory disorders encompass a range of conditions with varying levels of severity. Asthma, marked by chronic airway inflammation and hypersensitivity, is one such condition. It can lead to airway obstruction due to factors like bronchial spasms, mucosal edema, increased mucus secretion, or epithelial damage. Asthma triggers are diverse, ranging from allergens to emotional upset, and treatment focuses on both immediate relief through bronchodilators and long-term inflammation suppression.
Cancer Prevention02:59

Cancer Prevention

Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
Some...

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Related Experiment Video

Updated: Jul 15, 2026

Endobronchial Ultrasound-guided Intratumoral Injection of Cisplatin for the Treatment of Isolated Mediastinal Recurrence of Lung Cancer
04:04

Endobronchial Ultrasound-guided Intratumoral Injection of Cisplatin for the Treatment of Isolated Mediastinal Recurrence of Lung Cancer

Published on: February 12, 2017

Vaccines for lung cancer.

Edward A Hirschowitz1, David M Hiestand, John R Yannelli

  • 1Department of Internal Medicine, Division of Pulmonary and Critical Care Medicine, University of Kentucky Chandler Medical Center, Lexington, Kentucky 40536-0289, USA. eahirs2@uky.edu

Journal of Thoracic Oncology : Official Publication of the International Association for the Study of Lung Cancer
|April 6, 2007
PubMed
Summary

Active immunotherapy leverages the host immune system to combat cancer, offering a specific approach for widespread disease. While promising in lung cancer trials, its ultimate efficacy and optimal strategies require further investigation.

Related Experiment Videos

Last Updated: Jul 15, 2026

Endobronchial Ultrasound-guided Intratumoral Injection of Cisplatin for the Treatment of Isolated Mediastinal Recurrence of Lung Cancer
04:04

Endobronchial Ultrasound-guided Intratumoral Injection of Cisplatin for the Treatment of Isolated Mediastinal Recurrence of Lung Cancer

Published on: February 12, 2017

Area of Science:

  • Oncology
  • Immunology
  • Cancer Research

Background:

  • Immunotherapy exploits the immune system's ability to differentiate cancer cells from normal cells.
  • It presents a specific adjuvant approach with potential for minimal impact on healthy tissues.
  • Active immunotherapy utilizes the host's immune machinery for anti-tumor effects.

Purpose of the Study:

  • To review active immunotherapy strategies in cancer treatment.
  • To discuss the rationale, biological theory, and clinical application of these strategies.
  • To evaluate the current status and future directions of active immunotherapy in lung cancer.

Main Methods:

  • Literature review of active immunotherapy strategies.
  • Analysis of clinical trial data in lung cancer.
  • Discussion of biological mechanisms and clinical implementation.

Main Results:

  • Proof of principle for active immunotherapy in lung cancer is established in clinical trials.
  • No single superior approach has been identified to date.
  • The precise therapeutic efficacy of active immunotherapy remains to be determined.

Conclusions:

  • Active immunotherapy is a promising strategy for cancer treatment, particularly in lung cancer.
  • Further research is needed to define optimal approaches and establish definitive therapeutic efficacy.
  • Continued investigation into clinical implementation is crucial for advancing this field.