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Cellular engineering.

R M Nerem1

  • 1School of Mechanical Engineering, Georgia Institute of Technology, Atlanta 30332-0405.

Annals of Biomedical Engineering
|January 1, 1991
PubMed
Summary
This summary is machine-generated.

Cellular engineering merges engineering with cell biology for research and product development. This field utilizes cell culture and impacts tissue engineering and bioprocess engineering.

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Area of Science:

  • Cellular engineering
  • Biomedical engineering
  • Biotechnology

Background:

  • Emerging field at the intersection of engineering and cell/molecular biology.
  • Driven by the shift in biomedical engineering from organ/tissue to cellular/sub-cellular levels.
  • Relies heavily on advanced cell culture technologies for in vitro studies.

Purpose of the Study:

  • To define cellular engineering and its scope.
  • To highlight its role in basic research and applied product development.
  • To explore its interdisciplinary connections with tissue engineering and bioprocess engineering.

Main Methods:

  • Application of engineering principles to cell and molecular biology.
  • Utilizing cell culture technology for laboratory cultivation of living cells.

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  • Integration of recombinant DNA technology within bioprocess engineering.

    • Main Results:

    • Cellular engineering encompasses both fundamental research and the creation of cell-based products.
    • It plays a key role in tissue engineering for biological substitutes.
    • It is crucial for bioprocess engineering in manufacturing biochemical products.

    Conclusions:

    • Cellular engineering represents a significant expansion of biomedical engineering.
    • It shares intellectual ground with bioprocess engineering, particularly concerning mammalian cell applications.
    • This field transcends traditional biomedical engineering boundaries.