Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Biological response modifiers in cancer.

Purabi Reang1, Madhur Gupta, Kamlesh Kohli

  • 1Department of Pharmacology, Lady Hardinge Medical College, New Delhi-110001, India.

Medgenmed : Medscape General Medicine
|April 7, 2007
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Safe blood, strong nation - The journey of India's blood transfusion services: Under Ministry of Health and Family Welfare, Government of India.

Asian journal of transfusion science·2026
Same author

Patient knowledge and acceptance of radiation safety measures correlated to actual exposure records: A survey study.

Bioinformation·2026
Same author

Correlation between Biochemical Parameters and Radiographic Healing Score in Tibial Fractures.

Journal of orthopaedic case reports·2026
Same author

Comparative evaluation of the effect of non-surgical periodontal therapy on serum levels of mannose-binding lectin, SIRT-1 and C-reactive protein in non-smokers and smokers with stage III periodontitis: A case-control study.

Dental and medical problems·2025
Same author

"The feedback dilemma"-provider and learner perspectives regarding the barriers and facilitators for giving and receiving feedback in medical education: A parallel mixed methods approach.

Journal of education and health promotion·2024
Same author

Landscape assessment of the availability of medical abortion medicines in India.

Reproductive health·2024

Immunotherapy, including cytokines like interleukins (IL-2) and monoclonal antibodies, is increasingly used to treat cancer. Newer strategies like antiangiogenic agents and cancer vaccines show promise for activating immune responses against tumors.

Area of Science:

  • Oncology
  • Immunology
  • Pharmacology

Background:

  • Immunotherapy represents a significant advancement in cancer treatment.
  • Biological response modifiers can be used passively or actively to combat cancer.
  • Cytokines like interferons (IFNs) and interleukins (IL-2) are forms of nonspecific active immune stimulation.

Purpose of the Study:

  • To review the current landscape and emerging strategies in cancer immunotherapy.
  • To highlight the success of passive immunotherapy, particularly with monoclonal antibodies.
  • To discuss novel approaches including antiangiogenic agents and cancer vaccines.

Main Methods:

  • Review of existing literature on immunotherapy in cancer treatment.
  • Analysis of approved therapies and ongoing clinical trials.

Related Experiment Videos

  • Exploration of various immunomodulatory strategies.

    • Main Results:

    • Interleukin-2 (IL-2) is FDA-approved for renal cell carcinoma and metastatic colorectal cancer.
    • Bevacizumab, an anti-vascular endothelial growth factor (VEGF) agent, is approved for metastatic melanoma.
    • Monoclonal antibodies, antiangiogenic agents, and matrix metalloprotease inhibitors (MMPIs) have shown success.

    Conclusions:

    • Immunotherapy, encompassing both passive and active approaches, has demonstrated considerable success in cancer treatment.
    • Emerging strategies such as angiogenesis inhibitors and cancer vaccines hold significant potential for future cancer therapies.
    • The field is rapidly evolving with new agents and therapeutic strategies being developed to enhance cell-mediated immune responses against tumor antigens.