[II BAXTER-SENPE workshop: peripheral parenteral nutrition]

Area of Science:

• Clinical Nutrition
• Medical Devices
• Patient Safety

Background:

• Peripheral Parenteral Nutrition (PPN) is defined as parenteral nutrition compounded with carbohydrates, lipids, vitamins, and minerals.
• PPN administration via peripheral route prevents adverse effects associated with central venous access.
• PPN accounts for up to 50% of all prescribed parenteral nutrition in hospitals.

Framework:

• PPN composition: 60:40 carbohydrate to lipid ratio.
• Limited daily lipid intake: 1.3 g/kg body weight/day (≤30% of total calories).
• Maximum nitrogen load: 10 g nitrogen in 2500 mL volume.
• Osmolarity < 800 mOsm/L and pH 6.0-7.4 allow peripheral administration.

Implementation:

• Discussed by a multidisciplinary nutrition expert committee at the II BAXTER-SENPE workshop.
• Evaluated for indications, advantages, and drawbacks.
• Studies assess efficacy, safety, and pharmacoeconomics.

Implications:

• PPN is a valuable therapeutic resource for medical and surgical patients.
• Prevents metabolic-nutritional worsening.
• Significantly reduces complications, interventions, and hospital stay.