[Morphology of lymph nodes in secondary immunodeficiency provoked by acute diffuse peritonitis]

Lymph nodes of 30 patients operated because of acute diffuse peritonitis are studied histologically and immunologically. Two types of the lymph node response are found during the reactive stage. The response of the 1st type (the beginning of peritonitis) is characterized by the activation of T- and B-immunity systems. The signs of the depression are characteristic for the 2nd type. Immunodeficiency is enhanced in toxic and terminal stages. The most informative index of the immunodeficiency degree is a decrease of the ratio T-helper/T-suppressor cytotoxic lymphocytes. There is a close correlation between the state of patients and immunomorphological changes of lymph nodes and blood. Peritonitis results in the development of vitium cordis when intoxication associated with immune disturbances strengthens both the inflammation and intoxication.