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Updated: Jul 15, 2026

Real-time Observation of the DNA Strand Exchange Reaction Mediated by Rad51
06:24

Real-time Observation of the DNA Strand Exchange Reaction Mediated by Rad51

Published on: February 13, 2019

Homology-driven chromatin remodeling by human RAD54

Zhaoqing Zhang1, Hua-Ying Fan, Joseph A Goldman

  • 1Department of Molecular Biology, Massachusetts General Hospital and Department of Genetics, Harvard Medical School, 185 Cambridge Street, Boston, Massachusetts 02114, USA.

Nature Structural & Molecular Biology
|April 10, 2007
PubMed
Summary

Human RAD51 and RAD54 proteins facilitate DNA repair through homologous recombination. RAD54 protein remodeling of chromatin is essential for RAD51-mediated strand invasion, a crucial step in DNA double-strand break repair.

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