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Updated: Jul 15, 2026

Interventional Diagnostic Procedure: A Practical Guide for the Assessment of Coronary Vascular Function
Published on: March 15, 2022
[Invasive treatment of acute coronary syndrome in multiple affection of the coronary arteries]
Insights
For acute coronary syndrome (ACS) patients with multi-vessel coronary artery disease, one-stage coronary bypass surgery during ACS is more effective than staged procedures. This approach reduces mortality and coronary heart disease complications.
Area of Science:
- Cardiology
- Cardiovascular Surgery
- Interventional Cardiology
Context:
- Patients with acute coronary syndrome (ACS) and multi-vessel coronary artery disease often require invasive revascularization.
- Treatment strategies vary, including immediate multi-vessel coronary bypass (CB) or staged procedures involving angioplasty/stenting followed by later CB.
Purpose:
- To compare the effectiveness and risks of one-stage versus two-stage invasive revascularization in ACS patients with multi-vessel coronary artery disease.
Summary:
- A study compared one-stage coronary bypass (CB) during ACS (Group A, n=45) versus staged treatment (angioplasty/stenting then CB later, Group B, n=45).
- The one-stage CB approach during ACS demonstrated superior outcomes.
- Specifically, patients undergoing immediate multi-vessel CB experienced lower mortality and fewer coronary heart disease (CHD) complications.
Impact:
- The findings suggest that one-stage coronary bypass surgery during acute coronary syndrome is a more effective strategy for patients with multi-vessel coronary artery disease.
- This approach may lead to improved patient survival and reduced long-term cardiovascular morbidity.
- Results support the optimization of treatment pathways for ACS patients requiring complex revascularization.
Abstract:
A comparative assessment of the risk of invasive myocardial revascularizations in patients with multiple affection of coronary arteries and acute coronary syndrome (ACS) without stable ST-elevation on ECG was carried out. Group A (n=45) consisted of patients with one-stage revascularization with coronary bypass (CB) during ACS, group B (n=45) - balloon angioplasty /stenting of symptom-determining artery with subsequent CB in the "cold period" (6 months after ACS episode). It is demonstrated that the one-stage procedure (i.e. multiple CB during ACS) is more effective compared with two-stage invasive treatment because of lower lethality and lower rate of CHD complications.
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