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A New Single Chamber Implantable Defibrillator with Atrial Sensing: A Practical Demonstration of Sensing and Ease of Implantation
Published on: February 28, 2012
Permanent pacemaker and implantable cardioverter defibrillator infection: a population-based study
Daniel Z Uslan1, Muhammad R Sohail, Jennifer L St Sauver
1Department of Medicine, Division of Infectious Diseases, Mayo Clinic College of Medicine, 200 First Street SW, Rochester, MN 55905, USA. duslan@mednet.ucla.edu
Cardiac device infections are common, particularly with Staphylococcus aureus bloodstream infections (BSI). Patients with defibrillators have a higher infection rate than those with pacemakers.
Area of Science:
- Cardiology
- Infectious Diseases
- Epidemiology
Background:
- Cardiac device infection incidence is not well understood.
- Bloodstream infection (BSI) in patients with pacemakers or defibrillators may indicate device infection.
Purpose of the Study:
- To determine the incidence of cardiac device infection in a population-based cohort.
- To compare infection rates between pacemakers and defibrillators.
Main Methods:
- Retrospective, population-based cohort study (1975-2004) of adult cardiac device patients in Olmsted County, MN.
- Utilized the Rochester Epidemiology Project and standardized criteria to identify BSI and device infections.
- Calculated incidence using person-years of follow-up post-implantation.
Main Results:
- 1524 patients with cardiac devices were followed for 7578 person-years.
- The incidence of definite device infection was 1.9 per 1000 device-years.
- Device infection cumulative probability was higher for defibrillators than pacemakers (P<.001).
- Staphylococcus aureus BSI was associated with higher rates of definite or possible cardiac device infection (54.6%) compared to gram-negative bacilli BSI (12.0%).
Conclusions:
- This is the first population-based study to report cardiac device infection incidence.
- Cardiac device infection is common during Staphylococcus aureus BSI.
- Defibrillator recipients have a higher cardiac device infection rate than pacemaker recipients.
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