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Acute dystonia induced by sulpiride
G Linazasoro1, J F Martí Massó, B Olasagasti
1Sección Neurología, Hospital Ntra. Sra. Aránzazu, San Sebastián, Spain.
Clinical Neuropharmacology
|October 1, 1991
Summary
A 15-year-old boy experienced acute dystonic reactions, including oculogyric crises and retrocollis, after receiving sulpiride intravenously. Symptoms resolved with biperiden, highlighting sulpiride
Area of Science:
- Neurology
- Pharmacology
Background:
- Sulpiride is a medication used for certain psychiatric conditions.
- Neuroleptic drugs are known to cause extrapyramidal side effects.
Observation:
- A 15-year-old male presented with acute dystonic reactions after intravenous sulpiride administration.
- Manifestations included oculogyric crises, retrocollis, opisthotonus, and left arm/hand dystonia.
Findings:
- This case represents a previously undescribed side effect of sulpiride.
- The extrapyramidal symptoms were successfully reversed with biperiden treatment.
Implications:
- Sulpiride can induce extrapyramidal adverse reactions similar to classical neuroleptic drugs.
- Clinicians should be aware of the potential for dystonic reactions with sulpiride.
- Prompt recognition and treatment with anticholinergic agents like biperiden are crucial.