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Further studies on acid phosphatase in obese subjects
A Paggi1, P Borgiani, F Gloria-Bottini
1Chair of Human Development, 2nd University of Rome School of Medicine, Italy.
Disease Markers
|January 1, 1991
Abstract:
Low activity genetic variants of acid phosphatase (ACP1) are positively associated with extreme body mass deviations in obese subjects. The same pattern has been found in non-diabetic children, in diabetic pregnant women, and in non-diabetic adult subjects. Low activity variants of ACP1 also show a positive association with family history of obesity, supporting the hypothesis of an enhancing action of these variants on expressivity of obesity.