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Hydrocephalus in children born in 1999-2002: epidemiology, outcome and ophthalmological findings
Eva-Karin Persson1, Susann Anderson, Lars-Martin Wiklund
1Department of Paediatrics, Halmstad County Hospital, Halmstad, Sweden.
Insights
The incidence of hydrocephalus in children has decreased, but post-hemorrhagic hydrocephalus in extremely preterm infants has increased, leading to neurological issues. Ophthalmological abnormalities are common in affected children.
Area of Science:
- Pediatric Neurology
- Developmental Pediatrics
- Neuroscience
Background:
- Hydrocephalus is a significant neurological condition in children.
- Understanding its incidence and outcomes is crucial for effective management.
- Previous studies provide a baseline for current epidemiological trends.
Purpose of the Study:
- To monitor the incidence and outcomes of hydrocephalus in children.
- To compare current data with historical cohorts.
- To identify risk factors and associated morbidities.
Main Methods:
- Population-based prospective study in Western Sweden (1999-2002).
- Inclusion of all children diagnosed with hydrocephalus.
- Data collection via records, neuroimaging, and ophthalmological examinations.
- Comparison with a cohort from 1989-1998.
Main Results:
- Overall hydrocephalus incidence was 0.66 per 1,000 live births, with infantile hydrocephalus at 0.48 and hydrocephalus with myelomeningocele at 0.18.
- Incidence of hydrocephalus associated with myelomeningocele decreased compared to the previous decade.
- Ventriculo-peritoneal shunt was the primary treatment (42/54 children), with a high revision rate (61%).
- Neurological impairments affected 63% of children, more prevalent in preterm infants.
- Parenchymal lesion extent correlated with outcome.
- Ophthalmological abnormalities were found in 80%, with one-third experiencing visual impairment.
Conclusions:
- Incidence of post-hemorrhagic hydrocephalus in extremely preterm infants has risen, carrying a high risk of neurological sequelae.
- Ophthalmological abnormalities are frequent and require systematic assessment in all hydrocephalus cases.
- High morbidity and complication rates underscore the need for improved preventive and treatment strategies.
Objective:
The purpose of this study was to monitor incidence and outcome in children with hydrocephalus.
Materials And Methods:
This is a population-based prospective study of all the children with hydrocephalus born in western Sweden in 1999-2002. Etiological and clinical information was collected from records, neuroimaging and ophthalmological examinations. Comparisons with 208 children born in 1989-1998 were made.
Results:
The incidence was 0.66 per 1,000 live births, 0.48 for infantile hydrocephalus and 0.18 for hydrocephalus associated with myelomeningocele. The corresponding rates for 1989-1998 were 0.82, 0.49 and 0.33. Ventriculo-peritoneal shunt treatment was used in 42 of the 54 children and endoscopic third ventriculostomy in 12. Revisions were performed in 33 (61%). Neurological impairments were present in 63%, and they were more common in children born preterm than in those born at term. The radiological extent of parenchymal lesions correlated significantly with outcome. Ophthalmological abnormalities were found in 80%, including visual impairment in one third.
Conclusion:
The incidence of post-haemorrhagic hydrocephalus in children born extremely preterm increased; a group running a high risk of neurological sequelae. Ophthalmological abnormalities were frequent and need to be assessed in all children with hydrocephalus. The high rate of morbidity and complications necessitates the further development of preventive and treatment methods.
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