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BioWMS: a web-based Workflow Management System for bioinformatics.

Ezio Bartocci1, Flavio Corradini, Emanuela Merelli

  • 1Dipartimento di Matematica e Informatica, Università di Camerino, Via Madonna delle Carceri n,9, Camerino, MC, I-62032, Italy. ezio.bartocci@unicam.it

BMC Bioinformatics
|April 14, 2007
PubMed
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BioWMS is a novel Workflow Management System (WMS) enabling scientists to define and execute in-silico experiments via a web interface. This agent-based system offers a flexible and adaptable solution for bioinformatics workflows.

Area of Science:

  • Bioinformatics
  • Computational Biology
  • Scientific Workflow Management

Background:

  • In-silico experiments require reproducible and traceable workflows for data analysis.
  • Existing Workflow Management Systems (WMSs) often lack web-based interfaces and standardized process definition languages.
  • There is a need for flexible and reusable workflow solutions in bioinformatics.

Purpose of the Study:

  • To develop a web-based Workflow Management System (WMS) for in-silico experiments.
  • To enhance workflow reusability, reproducibility, and traceability.
  • To leverage agent-based technology for flexible and adaptive workflow enactment.

Main Methods:

  • Developed BioWMS, a Workflow Management System (WMS) with a web-based interface.

Related Experiment Videos

  • Implemented BioWMS using an agent-based middleware.
  • Dynamically generated domain-specific, agent-based workflow engines from user specifications.
  • Utilized agent proactiveness and mobility to embed domain features into agent behavior.

    • Main Results:

    • BioWMS supports definition, execution, and results management of in-silico experiments.
    • The system generates a multiagent system as a distributed, concurrent, and adaptive workflow engine.
    • BioWMS provides a user-friendly, web-based platform for workflow management.

    Conclusions:

    • BioWMS, powered by Hermes mobile computing middleware, ensures flexibility, scalability, and fault tolerance.
    • The system is suitable for workflow enactment in distributed and heterogeneous environments.
    • BioWMS facilitates interdisciplinary research in bioinformatics through standardized workflows.