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Updated: Feb 12, 2026

Author Spotlight: Exploring the Role of Unfolded Protein Response in HIV-1 Replication and Infectivity
Published on: June 14, 2024
The silent defense: micro-RNA directed defense against HIV-1 replication
1Department of Biochemistry & Molecular Biology, George Washington University, Washington, DC, USA. akumar@gwu.edu
Abstract:
MicroRNAs play critical role in regulating gene expression. MicroRNA profile of particular cell type bears the signature of cell type specific gene expression. Given that viral pathogens replicate by evading host defenses, research is now focused on the miRNA-regulated genes that critically regulate HIV-1 propagation in human host cells.
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