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Published on: February 23, 2014
Methicillin-resistant Staphylococcus aureus as a cause of community-acquired pneumonia
Curt Stankovic1, Prashant V Mahajan, Basim I Asmar
1Division of Emergency Medicine, Children's Hospital of Michigan, 3901 Beaubien, Detroit, MI 48201, USA. cstankov@dmc.org
Abstract:
New pathogens have emerged that now complicate the management of community-acquired pneumonia (CAP). Community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) has emerged as a potential cause of CAP, particularly complicated CAP. In this literature review, the incidence, invasiveness, and antimicrobial management of CA-MRSA is discussed. Based on existing data and the rising incidence of CA-MRSA, we recommend a change in antibiotic selection for complicated CAP.
Insights
Community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) is increasingly complicating community-acquired pneumonia (CAP). This review suggests updating antibiotic choices for complicated CAP due to rising CA-MRSA incidence and invasiveness.
Area of Science:
- Infectious Diseases
- Microbiology
- Pulmonology
Background:
- Community-acquired pneumonia (CAP) management is complicated by emerging pathogens.
- Community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) is a growing concern for CAP, especially severe cases.
Purpose of the Study:
- To review the incidence, invasiveness, and antimicrobial treatment of CA-MRSA in CAP.
- To recommend adjustments in antibiotic selection for complicated CAP based on current data.
Main Methods:
- Literature review of existing studies on CA-MRSA and CAP.
- Analysis of data on CA-MRSA incidence and clinical characteristics.
Main Results:
- CA-MRSA is an emerging pathogen in community-acquired pneumonia.
- Evidence suggests increasing incidence and invasiveness of CA-MRSA in CAP cases.
Conclusions:
- Current antibiotic strategies may be insufficient for complicated CAP due to CA-MRSA.
- A change in antibiotic selection for complicated CAP is recommended to address the threat of CA-MRSA.
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