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Updated: Jul 15, 2026

Ookluc: A Plasmodium berghei Line for Identifying Transmission-blocking Compounds
Published on: July 11, 2025
[New drugs against parasitic diseases]
Philippe M Loiseau1, Jacques Le Bras
1UMR 8076 CNRS, faculté de pharmacie, université de Paris-Sud XI, 92290 Châtenay-Malabry. philippe.loiseau@cep.u-psud.fr
Abstract:
The gap in the antiparasitic armamentarium is still not filled in 2006 and few original and useful drugs were marketed in the last decade. Against malaria, artemether combined with lumefantrine is adopted as first line therapy in a majority of endemic countries but still not available in France and several european countries. As its tolerance and efficacy are satisfactory, atovaquone-proguanil, is taking a major place for prevention and treatment in travellers. Liposomal amphothericin B and miltefosine extended the treatment of visceral leishmaniasis. Nitazoxanide and triclabendazole may be usefull in cryptosoridiosis or giardiasis and fasciolasis, respectively.
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