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Heart disease in psoriasis.

Hilal Maradit Kremers1, Marian T McEvoy, Frank J Dann

  • 1Division of Epidemiology, Department of Health Sciences Research, Mayo Clinic, Rochester, MN 55905, USA. maradit@mayo.edu

Journal of the American Academy of Dermatology
|April 17, 2007
PubMed
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Psoriasis is now understood as a systemic inflammatory condition, not just a skin disorder. This review explores the growing evidence linking psoriasis to an increased risk of heart disease.

Area of Science:

  • Immunology
  • Cardiology
  • Dermatology

Background:

  • Psoriasis was traditionally considered a skin-specific inflammatory disease.
  • Recent research highlights its immunopathogenesis and genetic links.
  • It is now recognized as a systemic inflammatory condition.

Purpose of the Study:

  • To review the evidence linking psoriasis to cardiovascular disease.
  • To identify gaps in current knowledge regarding this association.

Main Methods:

  • Literature review of studies on psoriasis and cardiovascular risk.
  • Analysis of current evidence on immunopathogenesis and genetics.

Main Results:

  • Psoriasis patients may face an elevated risk of heart disease.

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  • This association represents a significant, under-recognized cause of mortality.

    • Conclusions:

    • Psoriasis should be viewed as a systemic inflammatory condition with potential cardiovascular implications.
    • Further research is needed to fully understand and manage this increased cardiovascular risk.