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Updated: Jul 15, 2026

Demonstration of Heterologous Complexes formed by Golgi-Resident Type III Membrane Proteins using Split Luciferase Complementation Assay
Published on: September 10, 2020
Evidence for function of UDP galactose pyrophosphorylase in mice with absent galactose-1-phosphate uridyltransferase
Suzanne Wehrli1, Robert Reynolds, Stanton Segal
1NMR Core Facility, The Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA.
Abstract:
Mice with deletion of the galactose-1-phosphate uridyltransferase (GALT) gene were examined for their ability to form (13)C labeled hepatic UDP glucose from administered 1-(13)C galactose. NMR analysis of urinary acetaminophen glucuronide, which is derived from hepatic UDP glucose showed (13)C enrichment after concomitant administration of (13)C galactose and acetaminophen. The finding is consistent with the function of UDP galactose pyrophosphorylase as an alternate pathway of galactose metabolism.
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