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Related Experiment Videos

Relationship between bladder dysfunction and brain MRI in multiple sclerosis.

M G Grasso1, C Pozzilli, A Anzini

  • 1Department of Neurological Sciences, La Sapienza University, Rome, Italy.

Functional Neurology
|July 1, 1991
PubMed
Summary
This summary is machine-generated.

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Urinary dysfunction in multiple sclerosis (MS) is linked to brain changes. Midbrain lesions on MRI scans correlate significantly with urinary problems, suggesting the mesencephalic region

Area of Science:

  • Neurology
  • Urology
  • Radiology

Background:

  • Multiple sclerosis (MS) is a chronic neurological disease.
  • Urinary disturbances are common in MS patients.
  • The relationship between MS-related brain lesions and urinary symptoms requires further investigation.

Purpose of the Study:

  • To investigate the association between cerebral magnetic resonance imaging (MRI) findings and urinary disturbances in patients with multiple sclerosis (MS).

Main Methods:

  • Studied 70 consecutive patients diagnosed with definite multiple sclerosis (MS).
  • Assessed patients for the presence of urinary symptoms.
  • Correlated magnetic resonance imaging (MRI) findings of cerebral lesions with reported urinary disturbances.

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Main Results:

  • 32 subjects (46%) reported urinary symptoms, while 38 (54%) were asymptomatic.
  • Patients with urinary symptoms demonstrated greater overall functional disability.
  • A significant correlation was identified between the presence of midbrain lesions and urinary dysfunction.

Conclusions:

  • The mesencephalic formation (midbrain) may play a crucial role in maintaining urinary continence.
  • Midbrain lesions on MRI are associated with urinary disturbances in multiple sclerosis patients.
  • Further research into the neurological control of continence in MS is warranted.