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[Computerized analysis of brain perfusion parameter images].

B Turowski1, D Haenggi, H-J Wittsack

  • 1Diagnostische Radiologie/Neuroradiologie, Universitätsklinikum Düsseldorf. bernd.turowski@uni-duesseldorf.de

Rofo : Fortschritte Auf Dem Gebiete Der Rontgenstrahlen Und Der Nuklearmedizin
|April 17, 2007
PubMed
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This study introduces Angiotux 2D-ECCET, a computerized method for comparing brain perfusion parameters. It aids in the early diagnosis of cerebral vasospasm after subarachnoid hemorrhage.

Area of Science:

  • Neuroimaging
  • Medical Informatics
  • Radiology

Context:

  • Cerebral vasospasm following subarachnoid hemorrhage (SAH) poses a significant clinical challenge.
  • Early and accurate diagnosis is crucial for preventing irreversible brain damage.
  • Quantitative assessment of cerebral blood flow is essential for monitoring vasospasm.

Purpose:

  • To develop a computerized method for direct quantitative comparison of brain perfusion parameters.
  • To enable clear visualization of perfusion changes over time and across vascular territories.
  • To facilitate early diagnosis of cerebral vasospasm.

Summary:

  • The Angiotux 2D-ECCET software segments brain perfusion parameter images, assigning values to vascular territories.
  • Mean values are averaged per segment and displayed graphically, with time-course follow-up available.

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  • The method, initially developed for CT perfusion, is adaptable to other imaging modalities.

    • Impact:

    • Provides objective and reproducible analysis of brain perfusion parameters.
    • Enables precise comparison of perfusion data for diagnostic and research purposes.
    • Aims to serve as a basis for analyzing subtle perfusion changes indicative of impending vasospasm.