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Related Concept Videos

Hemorrhagic Stroke ll: Pathophysiology01:29

Hemorrhagic Stroke ll: Pathophysiology

A hemorrhagic stroke develops when a cerebral blood vessel ruptures, allowing blood to escape into the surrounding brain tissue, as in intracerebral hemorrhage (ICH), or into the subarachnoid space, as in subarachnoid hemorrhage (SAH). Because the skull is a rigid compartment, the sudden presence of extravascular blood rapidly increases intracranial pressure and compresses adjacent neural structures, leading to immediate tissue injury and impaired cerebral perfusion.Mass Effect and Primary...
Hemorrhagic Stroke l: Introduction01:17

Hemorrhagic Stroke l: Introduction

A hemorrhagic stroke is an acute neurological event that occurs when a weakened cerebral blood vessel ruptures, allowing blood to accumulate within or around the brain. The sudden release of blood forms a focal hematoma that increases intracranial pressure, displaces neural tissue, and can obstruct cerebrospinal fluid pathways. These effects may be compounded by intraventricular extension of the hemorrhage, cerebral edema, or compression of adjacent structures, all of which contribute to...
Cerebral Edema ll: Pathophysiology01:22

Cerebral Edema ll: Pathophysiology

Vasogenic edema is a major form of cerebral edema characterized by abnormal accumulation of fluid in the brain’s extracellular space due to disruption of the blood–brain barrier (BBB). The BBB is a specialized structure composed of endothelial cells connected by tight junctions, supported by astrocytic endfeet and a basement membrane. Under normal conditions, it tightly regulates the movement of ions, proteins, and solutes between the bloodstream and brain parenchyma. When this barrier loses...
Increased Intracranial Pressure l: Introduction01:14

Increased Intracranial Pressure l: Introduction

Intracranial hypertension is a sustained elevation of intracranial pressure (ICP) above 22 mm Hg. In supine adults, normal ICP is ~7–15 mm Hg.The rigid, nonexpandable cranium contains three components—brain tissue, blood, and cerebrospinal fluid (CSF)—that total ~1,700 mL in a typical adult: 1,400 mL brain (~80%), 150 mL blood (~10%), and 150 mL CSF (~10%). According to the Monro–Kellie doctrine, total intracranial volume is effectively fixed. When one component expands, CSF and venous blood...
Cerebral Edema l: Introduction01:19

Cerebral Edema l: Introduction

Cerebral edema is a pathological increase in brain water content that disrupts intracranial pressure regulation and impairs neurological function. Because the cranial vault is rigid, even modest increases in tissue volume can compromise cerebral perfusion, distort neural structures, and initiate secondary injury. Cerebral edema develops through four principal mechanisms: vasogenic, cytotoxic, interstitial, and ionic.Vasogenic EdemaVasogenic edema arises from disruption of the blood–brain...
Brain Abscess l: Introduction01:26

Brain Abscess l: Introduction

A brain abscess is a focal, intracerebral infection characterized by a localized collection of pus within the brain parenchyma, resulting from microbial invasion and the body’s inflammatory response. It progresses through stages: early and late cerebritis, followed by early and late capsule formation, reflecting tissue destruction, immune response, and eventual encapsulation.Etiology and PathogenesisCausative organisms vary with source and host factors, often involving polymicrobial infections,...

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Related Experiment Video

Updated: Jul 15, 2026

Pre-Chiasmatic, Single Injection of Autologous Blood to Induce Experimental Subarachnoid Hemorrhage in a Rat Model
09:14

Pre-Chiasmatic, Single Injection of Autologous Blood to Induce Experimental Subarachnoid Hemorrhage in a Rat Model

Published on: June 18, 2021

[Interhemispheric subdural haematoma].

Z Novák1, J Chrastina, T Kriva

  • 1Neurochirurgická klinika LF MU a FN u sv. Anny v Brne, Brno. zdenek.novak@fnusa.cz

Rozhledy V Chirurgii : Mesicnik Ceskoslovenske Chirurgicke Spolecnosti
|April 18, 2007
PubMed
Summary

Interhemispheric subdural hematomas are rare but require prompt surgical evacuation. Patient outcomes depend on initial condition and associated injuries, highlighting the need for vigilant monitoring.

Related Experiment Videos

Last Updated: Jul 15, 2026

Pre-Chiasmatic, Single Injection of Autologous Blood to Induce Experimental Subarachnoid Hemorrhage in a Rat Model
09:14

Pre-Chiasmatic, Single Injection of Autologous Blood to Induce Experimental Subarachnoid Hemorrhage in a Rat Model

Published on: June 18, 2021

Area of Science:

  • Neurosurgery
  • Neuroradiology
  • Trauma Surgery

Background:

  • Interhemispheric subdural hematoma (ISDH) is an uncommon neurosurgical finding, even with advanced imaging like computed tomography (CT).
  • ISDH can present with varied clinical symptoms, often influenced by associated traumatic brain injuries.

Purpose of the Study:

  • To report on a cohort of 14 patients surgically treated for interhemispheric subdural hematoma.
  • To analyze the clinical presentation, diagnostic methods, surgical interventions, and prognostic factors associated with ISDH.

Main Methods:

  • Retrospective review of 14 patients operated on for ISDH.
  • Diagnosis confirmed via CT scans.
  • Surgical evacuation performed through parasagittal osteoplastic craniotomy or burr hole trephination.

Main Results:

  • The majority of ISDH cases (13/14) were traumatic in origin.
  • Typical symptoms of medial cortical compression were not universally present; falx syndrome was the sole manifestation in two patients.
  • Patient outcomes were correlated with admission status and presence of hemorrhagic contusions.

Conclusions:

  • Surgical intervention is crucial for interhemispheric subdural hematoma.
  • Anticoagulation, coagulopathy, and admission clinical status are critical prognostic indicators.
  • Conservative management requires careful observation due to the risk of sudden clinical deterioration.