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Updated: Jul 10, 2026
08:49
Murine Ileocolic Bowel Resection with Primary Anastomosis
Published on: October 29, 2014
Irritable bowel syndrome and negative appendectomy: a prospective multivariable investigation
Ching-Liang Lu1, Chun-Chu Liu, Jong-Ling Fuh
1Division of Gastroenterology, Taipei Veterans General Hospital, School of Medicine, National Yang-Ming University, Taipei, Taiwan 11217. cllu@vghtpe.gov.tw
Gut
|April 19, 2007
Summary
Patients with Irritable Bowel Syndrome (IBS) and anxiety are more likely to undergo negative appendectomy (NA). Physicians should consider CT scans for suspected appendicitis, especially in IBS patients with atypical symptoms.
Area of Science:
- Gastroenterology
- Surgical Outcomes
- Diagnostic Accuracy
Background:
- Negative appendectomy (NA) rates vary, influenced by diagnostic challenges in suspected appendicitis.
- Irritable Bowel Syndrome (IBS) and psychological factors may impact clinical presentation and diagnostic pathways.
Purpose of the Study:
- To prospectively investigate associations between IBS, psychiatric profiles, quality of life, and clinical features with negative appendectomy (NA).
Main Methods:
- A longitudinal study of 430 patients undergoing surgery for suspected appendicitis.
- Utilized Rome-II IBS questionnaire, anxiety/depression scales, SF-36, and clinical/pathological/CT findings.
Main Results:
- NA patients (15.8%) were younger, predominantly female, with higher IBS prevalence, anxiety, and lower quality of life.
- Independent predictors for NA included IBS, anxiety, atypical pain, low polymorphonuclear cell percentage, and no CT scan use.
Conclusions:
- Patient factors (IBS, anxiety, atypical presentation) and physician factors (low CT scan usage) independently predict NA.
- Caution is advised for operating on IBS patients; CT scans are recommended for suspected appendicitis, especially with atypical symptoms and IBS.
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