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Stimulation of Notch Signaling in Mouse Osteoclast Precursors
08:01

Stimulation of Notch Signaling in Mouse Osteoclast Precursors

Published on: February 28, 2017

Regulation of lymphocyte development by Notch signaling

Kenji Tanigaki1, Tasuku Honjo

  • 1Research Institute, Shiga Medical Center, 5-4-30 Moriyama, Moriyama-shi, Shiga 524-8524 Japan.

Nature Immunology
|April 19, 2007
PubMed

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The Notch gene came into the limelight in 1914 after the discovery that its mutation in Drosophila melanogaster leads to a serrated (or "notched") wing margin phenotype. It was not until 1985...
Notch Signaling Pathway03:14

Notch Signaling Pathway

The Notch signaling pathway is a major intracellular signaling pathway that is highly conserved over a broad spectrum of metazoan species. It stands unique from other intracellular signaling mechanisms in animals because notch protein itself acts as the receptor as well as the primary signaling molecule.
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