Related Experiment Video
Updated: Jul 15, 2026

Personalized Peptide Arrays for Detection of HLA Alloantibodies in Organ Transplantation
Published on: September 6, 2017
14th International HLA and Immunogenetics Workshop: report on the structural basis of HLA compatibility
1Division of Transplantation Pathology, Thomas E. Starzl Transplantation Institute, University of Ptttsburgh Medical Center, Pittsburgh, PA 15261, USA. duquesnoyr@msx.upmc.edu
Abstract:
Under auspices of the 14th International Human Leukocyte Antigen (HLA) and Immunogenetics Workshop, multilaboratory collaborative studies were organized addressing the following projects: (1) identification of structurally defined class I and class II HLA epitopes by human monoclonal antibodies, (2) assessment of the relative immunogenicity of structurally defined donor HLA mismatches in kidney transplantation, and (3) evaluation of the usefulness of structurally based HLA matching in platelet transfusion support of alloimmunized thrombocytopenic patients. This progress report describes a preliminary HLAMatchmaker-based data analysis in each project. The findings support the clinical usefulness of structural HLA matching.
More Related Videos
10:37Analysis of HBV-Specific CD4 T-cell Responses and Identification of HLA-DR-Restricted CD4 T-Cell Epitopes Based on a Peptide Matrix
Published on: October 20, 2021
11:17Stability and Structure of Bat Major Histocompatibility Complex Class I with Heterologous β2-Microglobulin
Published on: March 10, 2021
Related Concept Videos
Antigens Involved in Adaptive Immunity
Complete Antigens
Complete antigens possess both immunogenicity and reactivity.
Tissue Transplantation
The Biology of Tissue Transplantation
The biology of tissue transplantation hinges on the Major Histocompatibility Complex (MHC) molecules. These molecules...