Related Experiment Video
Updated: Jul 15, 2026
13:33
Infinium Assay for Large-scale SNP Genotyping Applications
Published on: November 19, 2013
Population samples and genotyping technology.
S J Mack1, A Sanchez-Mazas, R M Single
1Children's Hospital Oakland Research Institute, Oakland, CA94501-1155, USA. steve.mack@contractors.roche.com
Tissue Antigens
|April 21, 2007
Summary
The 14th International Human Leukocyte Antigen (HLA) Immunogenetics Workshop characterizes global HLA diversity and its links to population history. New high-resolution genotype data from 112 global populations are being generated to advance this research.
Area of Science:
- Human Immunogenetics
- Population Genetics
- Anthropology
Background:
- The 14th International Human Leukocyte Antigen (HLA) Immunogenetics Workshop (14th-IHIWS) builds upon previous efforts.
- It continues the population sampling, genotype data generation, and biostatistic analyses from the 13th International Histocompatibility Workshop.
Purpose of the Study:
- To further characterize global HLA allele and haplotype diversity.
- To better describe the relationships between major histocompatibility complex diversity, geography, linguistics, and population history.
Main Methods:
- Recruiting new investigators to the project.
- Generating new high-resolution class I and class II genotype data.
- Analyzing data from 112 population samples worldwide.
Main Results:
- Ongoing generation of high-resolution HLA genotype data for 112 diverse global populations.
- Continued biostatistical analyses to interpret genetic diversity patterns.
Conclusions:
- The project aims to enhance understanding of human genetic diversity and population history through HLA studies.
- Findings will contribute to characterizing the complex interplay between HLA, geography, and human evolution.
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