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Updated: Jul 15, 2026
07:35
Assessment of Open Probability of the Mitochondrial Permeability Transition Pore in the Setting of Coenzyme Q Excess
Published on: June 1, 2022
Measurement of membrane permeability and the permeability transition of mitochondria
Naoufal Zamzami1, Carine Maisse, Didier Métivier
1INSERM U848, Université Paris Sud, Institut Gustave Roussy, F-94805 Villejuif, France.
Methods in Cell Biology
|April 21, 2007
Abstract
No abstract available in PubMed .
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A single mitochondrion is a bean-shaped organelle enclosed by a double-membrane system. The outer membrane of mitochondria is smooth and contains many porins - the integral membrane transporters. Porins enable free diffusion of ions and small uncharged molecules through the outer mitochondrial membrane but limit the transport of molecules larger than 5000 Daltons. Further, the outer mitochondrial membrane forms a unique structure called membrane contact sites with other subcellular organelles,...
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