Related Experiment Video
Updated: Jul 15, 2026

The Motivation for Alcohol Reward: Predictors of Progressive-Ratio Intravenous Alcohol Self-Administration in Humans
Published on: April 28, 2022
The relationship between prospective self-rating of alcohol sensitivity and craving and experimental results from two
Lara A Ray1, Shaneen Meskew-Stacer, Kent E Hutchison
1University of Colorado, Department of Psychology, Boulder, CO, USA. lara_ray@brown.edu
Objective:
Determining whether individuals can provide accurate reports of alcohol sensitivity and craving, outside of a laboratory alcohol challenge, has important research and clinical implications. The primary goals of the present study are (1) to test the relationship between prospective self-ratings of the effects of alcohol and alcohol craving, and experimental results from alcohol challenge studies and (2) to examine potential moderators of that relationship.
Method:
Participants were heavy drinkers who completed either an intravenous (n = 49) or an oral administration (n = 135) alcohol challenge. Participants were asked to estimate their craving for alcohol in a drinking situation and their subjective intoxication after consuming three drinks. Subjective intoxication and alcohol craving were then assessed during the laboratory alcohol challenge.
Results:
Estimated subjective intoxication and alcohol craving were significant predictors of subjective intoxication and craving measured under laboratory conditions and accounted for, at most, 16% and 37%, respectively, of the variance in laboratory measures.
Conclusions:
Taken together, these findings suggest that sensitivity to the effects of alcohol and alcohol craving may be measured outside of the laboratory but that scales that are especially designed for nonlaboratory studies may be required.
More Related Videos
08:05A Prediction Error-driven Retrieval Procedure for Destabilizing and Rewriting Maladaptive Reward Memories in Hazardous Drinkers
Published on: January 5, 2018
13:24A Procedure to Observe Context-induced Renewal of Pavlovian-conditioned Alcohol-seeking Behavior in Rats
Published on: September 19, 2014