Related Experiment Video
Updated: Jul 15, 2026

Electrochemiluminescence Assays for Human Islet Autoantibodies
Published on: March 23, 2018
Anti-diabetic activity of Aloe excelsa
M Gundidza1, S Masuku, G Humphrey
1Department of Pharmacy, University of Zimbabwe, Mount Pleasant, Harare, Zimbabwe.
Objective:
To investigate the effect of Aloe excelsa powder on diabetes.
Design:
The experiment was carried out in the laboratory on both normal and diabetic rats. Diabetes was induced in the rats by using streptozotocin. Thereafter, blood samples were taken from both the normal and diabetic rats and the sugar levels measured by using the Accutrend Alpha blood glucose monitoring kit.
Setting:
The experiment was conducted in the laboratory in the Faculty of Medicine at the University of Zimbabwe.
Subjects:
A total of 280 male albino rats weighing 250 g on average were used. They were obtained from the Animal House of the Medical School at the University of Zimbabwe.
Main Outcome Measures:
Reduction in sugar levels.
Results:
The Aloe excelsa powder produced a dose-dependent reduction in the blood glucose in blood glucose levels. It also compared well with the effect of insulin.
Conclusion:
This study shows that Aloe excelsa has significant activity on glucose levels in rats and this, therefore, confirms the claims by traditional healers that this plant has anti-diabetic effects.
More Related Videos
14:18Dioscin Mediated IgA Nephropathy Alleviation by Inhibiting B Cell Activation In Vivo and Decreasing Galactose-Deficient IgA1 Production In Vitro
Published on: October 13, 2023
11:31High-Efficiency Generation of Antigen-Specific Primary Mouse Cytotoxic T Cells for Functional Testing in an Autoimmune Diabetes Model
Published on: August 16, 2019
Related Concept Videos
Type I Diabetes I: Introduction
Diabetes Mellitus: Introduction
Diabetes: Symptoms, Diagnosis, and Complications
Type I Diabetes II: Pathophysiology
Enzyme-Linked Immunosorbent Assay
There are many different types of ELISAs, but they all involve an antibody molecule whose constant region binds an enzyme, leaving the variable region free to bind its specific antigen. Enzyme-substrate reaction allows the antigen to be visualized or quantified.
Cross-reactivity