Related Experiment Video
Updated: Jul 15, 2026
Human Blastocyst Biopsy and Vitrification
Published on: July 26, 2019
Heterotopic abdominal pregnancy following two-blastocyst embryo transfer
Jaime M Knopman1, Sheeva Talebian, Debbra A Keegan
1Department of OB/GYN, NYU Medical Center, New York, New York 10016, USA. jaimeknopman@gmail.com
Objective:
To report a case of a heterotopic primary abdominal pregnancy after two-blastocyst IVF-ET.
Design:
Case report.
Setting:
University-based IVF program.
Patient(S):
A woman with a heterotopic abdominal pregnancy after IVF-ET.
Intervention(S):
Pituitary down-regulation with luteal antagon, ovulation induction with menotropins, IVF-ET, progesterone in oil for luteal support, dilation and curettage for missed abortion, laparoscopy, and resection of abdominal gestation.
Main Outcome Measure(S):
Human chorionic gonadotropin levels, pelvic ultrasound examinations, and laparoscopic and pathologic findings.
Result(S):
A heterotopic abdominal pregnancy occurred after a two-blastocyst IVF-ET. The concurrent intrauterine gestation resulted in a miscarriage.
Conclusion(S):
The number of embryos transferred has been identified as a powerful risk factor for heterotopic pregnancy; however, heterotopic pregnancy can occur following a two-embryo, blastocyst stage transfer.
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