Related Experiment Video
Updated: Jul 15, 2026
Spontaneous Murine Model of Anaplastic Thyroid Cancer
Published on: February 3, 2023
Ameloblastic carcinoma: an analysis of 14 cases
James M Hall1, Dwight R Weathers, K Krishnan Unni
1Division of Anatomic Pathology, Mayo Clinic, Rochester, MN 55905, USA.
Objectives:
To present the classifications of malignant ameloblastomas, provide histopathologic guidelines for the diagnosis of ameloblastic carcinoma, and discuss treatment and long-term follow-up.
Study Design:
Fourteen archival specimens of ameloblastic carcinoma with detailed treatment and follow-up documentation were identified by the authors.
Results:
Traditional methods of microscopic observation form the basis for diagnosis. Histopathologic features of ameloblastic carcinoma include lack of differentiation, hypercellularity, high mitotic index, vascular invasion, and neural invasion.
Conclusion:
The long-term follow-up findings in this study support the concept that aggressive surgical intervention provides the best chance for survival. Patients treated otherwise had recurrence. The patients with the highest number of recurrences did not survive the disease.