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Ramadan fasting and thyroid hormone profile.

K M Sajid1, M Akhtar, G Q Malik

  • 1Atomic Energy Medical Centre, Multan.

JPMA. the Journal of the Pakistan Medical Association
|September 1, 1991
PubMed
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Fasting during Ramadan caused a gradual rise in thyroid-stimulating hormone (TSH) levels in adults, though levels remained normal. Triiodothyronine (T3) and thyroxine (T4) levels showed no significant changes during the fasting period.

Area of Science:

  • Endocrinology
  • Metabolic studies
  • Nutritional science

Background:

  • Fasting, particularly during Ramadan, involves significant dietary and metabolic changes.
  • Thyroid hormones (T3, T4) and TSH play crucial roles in regulating metabolism.
  • The impact of Ramadan fasting on thyroid function requires further investigation.

Purpose of the Study:

  • To investigate the effects of Ramadan fasting on thyroid hormone levels.
  • To compare thyroid-stimulating hormone (TSH), triiodothyronine (T3), and thyroxine (T4) levels during fasting versus non-fasting states.

Main Methods:

  • A longitudinal study involving 46 participants (41 males, 5 females, aged 28-56).
  • Blood samples were collected before, during, and after the Ramadan fasting period (6 samples per individual).

Related Experiment Videos

  • Assayed TSH, T3, and T4 levels to assess thyroid function changes.

    • Main Results:

    • A significant, gradual increase in TSH levels was observed throughout the fasting month.
    • Mean TSH levels remained within established normal physiological ranges.
    • No significant alterations were detected in T3 and T4 levels during the fasting period.

    Conclusions:

    • Ramadan fasting induces a modest, yet statistically significant, rise in TSH levels.
    • Thyroid hormone levels (T3 and T4) are not significantly affected by Ramadan fasting.
    • Post-fasting thyroid function returns to pre-fasting levels.