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Updated: Jul 15, 2026
Stereotactic Radiosurgery for Gynecologic Cancer
Published on: April 17, 2012
Corpus callosotomy using conformal stereotactic radiosurgery
M A Celis1, S Moreno-Jiménez, J M Lárraga-Gutiérrez
1Unidad de Radioneurocirugía, Instituto Nacional de Neurología y Neurocirugía, Insurgentes sur 3877, La Fama, Tlalpan, 14269, México, D.F., México. macelisl@yahoo.com.mx
Objects:
To show the clinical results of a corpus callosotomy (CC) treatment using conformal stereotactic radiosurgery (SRS) on a patient with medically intractable multifocal epilepsy.
Materials And Methods:
A 17-year-old male patient underwent corpus callosotomy conformal SRS using a dedicated linear accelerator (linac) with dynamic arcs technique. The prescribed dose was 36.0 Gy at the periphery of the rostrum, genu, and a half of the body of the corpus callosum (CCA). At 8 months after conformal SRS, the patient developed a significant brain edema and moderate transitory motor deficit, which were controlled with steroids. After 32 months follow-up, there is an improvement of 84% on drop attacks and generalized tonic-clonic seizures.
Conclusions:
Conformal SRS for corpus callosotomy with a single isocenter reproduce the results reported on literature using Gamma Knife-based SRS. The results show that this technique is safe and demonstrate its efficacy to control seizures.
