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Updated: Jan 28, 2026

A Rehabilitation Program of Exoskeleton-assisted Body Weight-Supported Treadmill Training with Non-immersive Virtual Reality for Stroke Patients
Published on: May 16, 2025
Locomotor training using body weight support on a treadmill improves mobility in persons with multiple sclerosis: a
Barbara Giesser1, Janell Beres-Jones, Amy Budovitch
1Department of Neurology, UCLA School of Medicine, Los Angeles, CA 90095, USA. bgiesser@mednet.ucla.edu
Locomotor training using body weight support on a treadmill (LTBWST) is safe for multiple sclerosis (MS) patients. This therapy may improve muscle strength, balance, and walking ability in individuals with MS.
Area of Science:
- Neurology
- Rehabilitation Medicine
- Physical Therapy
Background:
- Multiple sclerosis (MS) is a chronic neurological disease.
- Impaired ambulation is a common and debilitating symptom in MS.
- Locomotor training is a potential therapeutic approach for improving mobility.
Purpose of the Study:
- To investigate the benefits of locomotor training using body weight support on a treadmill (LTBWST).
- To assess the tolerability of LTBWST in individuals with MS.
Main Methods:
- Four participants with advanced MS (EDSS 7.0-7.5) and impaired ambulation were enrolled.
- Subjects underwent an average of 40 LTBWST sessions over several months.
Main Results:
- Significant improvements were observed in muscle strength, spasticity, endurance, and balance.
- Participants demonstrated enhanced walking speed and improved quality of life.
- LTBWST was well-tolerated, with no reported fatigue or adverse effects.
Conclusions:
- LTBWST is a safe and well-tolerated intervention for individuals with MS.
- This training approach shows potential for improving functional mobility parameters in MS patients.
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