Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Cefixime. Microbiologic, kinetic and clinical profile].

F Di Nola1, R Arione, C Bramato

  • 1Ospedale Amedeo di Savoia, Torino.

Minerva Medica
|October 1, 1991
PubMed
Summary

Cefixime, a third-generation cephalosporin antibiotic, shows high activity against Gram-negative bacteria and specific Gram-positive strains. Its favorable pharmacokinetics and once-daily dosing make it a valuable option for respiratory tract infections.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Tenofovir plasma concentrations according to companion drugs: a cross-sectional study of HIV-positive patients with normal renal function.

Antimicrobial agents and chemotherapy·2013
Same author

Colonization of a water system by Legionella organisms and nosocomial legionellosis: a 5-year report from a large Italian hospital.

Infection control and hospital epidemiology·2006
Same author

[Quality of data or quality of care? Comparison of diverse standarization methods by clinical severity, based on the discharge form, in the analysis of hospital mortality].

Epidemiologia e prevenzione·2000
Same author

[Social class, mode of admission, severity of illness and hospital mortality: an analysis with "All patient refined DRG" of discharges from the Molinette hospital in Turin].

Epidemiologia e prevenzione·1999
Same author

[Psychiatric disease in patients with HIV infections hospitalized in a ward for prisoners].

Minerva medica·1993
Same author

[Treatment of chronic hepatitis with interferon-beta].

Minerva medica·1993

Area of Science:

  • Microbiology
  • Pharmacology
  • Clinical Medicine

Context:

  • Evaluation of cefixime, an oral third-generation cephalosporin.
  • Assessment of its microbiological spectrum, pharmacokinetic properties, and clinical utility.

Purpose:

  • To present the comprehensive profile of cefixime.
  • To highlight its efficacy and suitability for specific infections.

Summary:

  • Cefixime exhibits potent activity against Gram-negative aerobic bacteria and key Gram-positive cocci (e.g., Streptococcus pneumoniae).
  • It demonstrates no activity against anaerobic bacteria.
  • The antibiotic possesses favorable pharmacokinetic properties, including good tissue distribution, and is indicated for upper and lower respiratory tract infections caused by susceptible pathogens like H. influenzae and B. catarrhalis.

Related Experiment Videos

Impact:

  • Cefixime expands therapeutic options for bacterial infections.
  • Its once-daily dosing regimen enhances patient compliance.
  • Provides a new, effective antibiotic for common respiratory infections.