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Updated: Jul 15, 2026

A Non-invasive Way to Isolate and Phenotype Cells from the Conjunctiva
Published on: July 5, 2017
[Impression cytology in patients with dry eye syndrome and various rheumatic diseases]
Monika Oziebło-Kupczyk1, Dorota Sredzińska-Kita, Karol Kita
1Klinika Okulistyki Ozieciecej Akademii Medycznej w Białymstoku.
Purpose:
The aim of this study was to evaluate the cytological changes of bulbar conjunctiva in patients with various rheumatic diseases and dry eye syndrome.
Material And Methods:
60 patients with rheumatoid arthritis (RA), systemic scleroderma (SScl), primary Sjbgren syndrome (pSS), systemic lupus erythematosus (SLE) and dry eye syndrome were studied. The ocular examination consisted of Schirmer I, break- up time of tear film (BUT), fluorescein and lissamine green staining and impression cytology of bulbar conjunctiva.
Results And Conclusions:
The morphological alternations of bulbar conjunctiva seen in impression cytology specimens correlated with clinical signs of dry eye syndrome.
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